Esophageal and Gastric Stricture Formation Following Corrosive Ingestion in Our Local Population

Esophageal and Gastric Stricture Formation

Authors

  • Asfand-e-Yar Khan Primary Health Services, Nowshera, Pakistan
  • Sadaf Abdullah MTI Lady Reading Hospital, Peshawar, Pakistan
  • . Kamran Primary Health Services, Charsadda, Pakistan
  • Zubair Ejaz Primary Health Services, Nowshera, Pakistan
  • Muhammad Sohail Primary Health Services, Mardan, Pakistan
  • Abubakkar Alam Alkhidmat Hospital, Peshawar, Pakistan
  • Inam Ullah Primary Health Services, Mardan, Pakistan
  • Syeda Rubina Gillani Primary Health Services, Nowshera, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i03.635

Keywords:

Esophageal and Gastric Stricture Formation

Abstract

Corrosive substances are defined as chemicals which cause injury upon coming in contact with living tissues such as the skin, gastrointestinal tract, respiratory tract and eyes. These include acids, alkalis, oxidizing agents, hydrocarbons among others. Objective: To determine the frequency and difference in the frequency of upper gastrointestinal stricture formation following corrosive ingestion in the gastroenterology unit of Lady Reading Hospital, Peshawar. Methods: This cross- sectional study was held in the Gastroenterology unit of Lady Reading Hospital, Peshawar from 16th July, 2019 to 16th Jan, 2019. Detailed history was taken from the patient and the container of the chemical ingested was examined to find out the duration since ingestion, amount of chemical ingested, and the type of chemical ingested (acid or alkali). Results: Mean and SD for age was 35 ± 5.55. Mean and SDs for duration since ingestion. Mean and SDs for amount of corrosive ingestion was 24 ± 1.54. 50 (34.48%) patients were recorded in 10-25 years’ age group and 95 (65.51%) patients were recorded in 26-40 years’ age group. 97 (66.89%) patients were male, and 48 (33.10%) patients were female. 41 (28.27%) patients had acidic corrosion and 104 (71.72%) patients had alkali corrosion. As per frequencies and percentages for stricture formation, 57 (39.31%) patients had stricture formation. Conclusions: Although the mortality and morbidity of corrosive gastric injuries is high, the key to improve the survival is early identification of perforation, maintenance of nutrition and control of sepsis.

References

Lupa M, Magne J, Guarisco JL, Amedee R. Update on the diagnosis and treatment of caustic ingestion. Ochsner Journal. 2009 Jun 20; 9(2): 54-9.

Bonavina L, Chirica M, Skrobic O, Kluger Y, Andreollo NA, Contini S, Simic A, Ansaloni L, Catena F, Fraga GP, Locatelli C. Foregut caustic injuries: results of the world society of emergency surgery consensus conference. World Journal of Emergency Surgery. 2015 Dec; 10(1): 1-0. doi: 10.1186/s13017-015-0039-0.

Park KS. Evaluation and management of caustic injuries from ingestion of acid or alkaline substances. Clinical Endoscopy. 2014 Jul; 47(4): 301-7. doi: 10.5946/ce.2014.47.4.301.

Contini S, Scarpignato C. Caustic injury of the upper gastrointestinal tract: a comprehensive review. World Journal of Gastroenterology: WJG. 2013 Jul; 19(25): 3918. doi: 10.3748/wjg.v19.i25.3918.

Kluger Y, Ishay OB, Sartelli M, Katz A, Ansaloni L, Gomez CA, Biffl W, Catena F, Fraga GP, Di Saverio S, Goran A. Caustic ingestion management: world society of emergency surgery preliminary survey of expert opinion. World Journal of Emergency Surgery. 2015 Dec; 10: 1-8. doi: 10.1186/s13017-015-0043-4.

Katz A and Kluger Y. Caustic material ingestion injuries-paradigm shift in diagnosis and treatment. Health Care Current Reviews. 2015; 3(3):152. doi: 10.4172/2375-4273.1000152.

Lingala R and Kota R. Study of corrosive poisoning and its effects on upper gastrointestinal tract and surgical management–A single institution experience. Journal of Evidence Based Medicine and Healthcare. 2017; 4: 2691-5. doi: 10.18410/jebmh/2017/535.

Temiz A, Oguzkurt P, Ezer SS, Ince E, Hicsonmez A. Predictability of outcome of caustic ingestion by esophagogastroduodenoscopy in children. World Journal of Gastroenterology: WJG. 2012 Mar; 18(10): 1098. doi: 10.3748/wjg.v18.i10.1098.

Usta M, Erkan T, Cokugras FC, Urganci N, Onal Z, Gulcan M, et al. High doses of methylprednisolone in the management of caustic esophageal burns. Pediatrics. 2014 Jun; 133(6): e1518-24. doi: 10.1542/peds.2013-3331.

Ahtaridis G, Snape WJ, Cohen S. Clinical and manometric findings in benign peptic strictures of the esophagus. Digestive Diseases and Sciences. 1979 Nov; 24: 858-61. doi: 10.1007/BF01324902.

Lawson JD, Otto K, Grist W, Johnstone PA. Frequency of esophageal stenosis after simultaneous modulated accelerated radiation therapy and chemotherapy for head and neck cancer. American Journal of Otolaryngology. 2008 Jan; 29(1): 13-9. doi: 10.1016/j.amjoto.2006.12.002.

Chen AM, Li BQ, Jennelle RL, Lau DH, Yang CC, Courquin J, et al. Late esophageal toxicity after radiation therapy for head and neck cancer. Head & Neck: Journal for the Sciences and Specialties of the Head and Neck. 2010 Feb; 32(2): 178-83. doi: 10.1002/hed.21164.

Pace F, Antinori S, Repici A. What is new in esophageal injury (infection, drug-induced, caustic, stricture, perforation)?. Current Opinion in Gastroenterology. 2009 Jul; 25(4): 372-9. doi: 10.1097/MOG.0b013e32832ad2e4.

Zografos GN, Georgiadou D, Thomas D, Kaltsas G, Digalakis M. Drug-induced esophagitis. Diseases of the Esophagus. 2009 Nov; 22(8): 633-7. doi: 10.1111/j.1442-2050.2009.00972.x.

Ono S, Fujishiro M, Niimi K, Goto O, Kodashima S, Yamamichi N, et al. Predictors of postoperative stricture after esophageal endoscopic submucosal dissection for superficial squamous cell neoplasms. Endoscopy. 2009 Aug; 41(08): 661-5. doi: 10.1055/s-0029-1214867.

Vega KJ, Chisholm S, Jamal MM. Comparison of reflux esophagitis and its complications between African Americans and non-Hispanic whites. World Journal of Gastroenterology: WJG. 2009 Jun; 15(23): 2878. doi: 10.3748/wjg.15.2878.

Liu SY, Xiao P, Li TX, Cao HC, Mao AW, Jiang HS, et al. Predictor of massive bleeding following stent placement for malignant oesophageal stricture/fistulae: a multicentre study. Clinical Radiology. 2016 May; 71(5): 471-5. doi: 10.1016/j.crad.2016.02.001.

Ravich WJ. Endoscopic management of benign esophageal strictures. Current Gastroenterology Reports. 2017 Oct; 19: 1-8. doi: 10.1007/s11894-017-0591-8.

Dakkak M, Hoare RC, Maslin SC, Bennett JR. Oesophagitis is as important as oesophageal stricture diameter in determining dysphagia. Gut. 1993 Feb; 34(2): 152-5. doi: 10.1136/gut.34.2.152.

Smith PM, Kerr GD, Cockel R, Ross BA, Bate CM, Brown P, et al. A comparison of omeprazole and ranitidine in the prevention of recurrence of benign esophageal stricture. Gastroenterology. 1994 Nov; 107(5): 1312-8. doi: 10.1016/0016-5085(94)90532-0.

Marks RD, Richter JE, Rizzo J, Koehler RE, Spenney JG, Mills TP, et al. Omeprazole versus H2-receptor antagonists in treating patients with peptic stricture and esophagitis. Gastroenterology. 1994 Apr; 106(4): 907-15. doi: 10.1016/0016-5085(94)90749-8.

Swarbrick ET, Gough AL, Foster CS, Christian J, Garrett AD, Langworthy CH. Prevention of recurrence of oesophageal stricture, a comparison of lansoprazole and high-dose ranitidine. European Journal of Gastroenterology & Hepatology. 1996 May; 8(5): 431-8.

Silvis SE, Farahmand M, Johnson JA. A randomized blinded comparison of omeprazole and ranitidine in the treatment of chronic esophageal stricture secondary to acid peptic esophagitis. Gastrointestinal Endoscopy. 1996 Mar; 43(3): 216-21. doi: 10.1016/S0016-5107(96)70319-X.

de Wijkerslooth LR, Vleggaar FP, Siersema PD. Endoscopic management of difficult or recurrent esophageal strictures. American Journal of Gastroenterology. 2011 Dec. 106(12): 2080-91. doi: 10.1038/ajg.2011.348.

Fan Y, Song HY, Kim JH, Park JH, Ponnuswamy I, Jung HY, et al. Fluoroscopically guided balloon dilation of benign esophageal strictures: incidence of esophageal rupture and its management in 589 patients. AJR-American Journal of Roentgenology. 2011 Dec; 197(6): 1481. doi: /10.2214/AJR.11.6591.

Al-Hussaini A. Savary dilation is safe and effective treatment for esophageal narrowing related to pediatric eosinophilic esophagitis. Journal of Pediatric Gastroenterology and Nutrition. 2016 Nov; 63(5): 474. doi: 10.1097/MPG.0000000000001247.

Sánchez G. Endoscopic dilatation of caustic esophageal strictures. Gastroenterologia y Hepatologia. 2003 Mar; 26(3): 147-51.

Shao YX, Chen ZH, Ning JW. Treatment of esophageal stricture and leakage with dilation stents. Shijie Huaren Xiaohua Zazhi 2002; 10: 249-251.

Lan LC, Wong KK, Lin SC, Sprigg A, Clarke S, Johnson PR, et al. Endoscopic balloon dilatation of esophageal strictures in infants and children: 17 years’ experience and a literature review. Journal of Pediatric Surgery. 2003 Dec; 38(12): 1712-5. doi: 10.1016/j.jpedsurg.2003.08.040.

Erdoğan E, Eroğlu E, Tekant G, Yeker Y, Emir H, Sarimurat N, et al. Management of esophagogastric corrosive injuries in children. European Journal of Pediatric Surgery. 2003 Oct; 13(05): 289-93.

Sugrue M, Sahebally SM, Ansaloni L, Zielinski MD. Grading operative findings at laparoscopic cholecystectomy-a new scoring system. World Journal of Emergency Surgery. 2015 Dec; 10(1): 1-8. doi: 10.1186/s13017-015-0005-x.

Park KS. Evaluation and management of caustic injuries from ingestion of acid or alkaline substances. Clinical Endoscopy. 2014 Jul; 47(4): 301-7. doi: 10.5946/ce.2014.47.4.301.

Downloads

Published

2023-03-31
CITATION
DOI: 10.54393/pjhs.v4i03.635
Published: 2023-03-31

How to Cite

Khan, A.- e-Y. ., Abdullah, S. ., Kamran, ., Ejaz, Z. ., Sohail, M. ., Alam, A. ., Ullah, I. ., & Gillani, S. R. . (2023). Esophageal and Gastric Stricture Formation Following Corrosive Ingestion in Our Local Population: Esophageal and Gastric Stricture Formation. Pakistan Journal of Health Sciences, 4(03), 68–72. https://doi.org/10.54393/pjhs.v4i03.635

Issue

Section

Original Article

Plaudit

Most read articles by the same author(s)