Association Between Nurses’ Knowledge and Practice Regarding Chemotherapy Induced Peripheral Neuropathy and Its Development in Cancer Patients: Chemotherapy Induced Peripheral Neuropathy

Muhammad  Ahmed Sohail; Muhammad  Afzal; Adnan  Yaqoob

doi:10.54393/pjhs.v3i07.473

Authors

Muhammad Ahmed Sohail Lahore School of Nursing, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
Muhammad Afzal Lahore School of Nursing, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
Adnan Yaqoob Lahore School of Nursing, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v3i07.473

Keywords:

Chemotherapy, Neuropathy Development, Knowledge, Practice, Cancer, Nurses, CIPN

Abstract

The adverse effects of peripheral neuropathy caused by chemotherapy include numbness, tingling, irritation, burning, difficulty keeping balance, and a chilling sensation. CIPN is one of the symptoms that has the potential to negatively impact the patient's quality of life (QoL), the treatment plan, and their overall safety. Objectives: To determine oncology nurses’ knowledge and practice regarding chemotherapy-induced peripheral neuropathy (CIPN) and its development in cancer patient. Methods: In a descriptive cross-sectional study, 172 registered nurses from two public hospitals were chosen with convenient sampling to see if there was an association between their knowledge and practice about chemotherapy-induced peripheral neuropathy in regard with its development in cancer patients. Three revised questioners were used to get information about nurses’ knowledge, practice and 1 questioner from patient about neuropathy development. (Knowledge, practice and neuropathy devolvement). Results: Knowledge showed that 56.4 % of participants had fair knowledge and Practice showed that 49.4 % of participants had fair practice, while 47.1% of patient had developed mild neuropathy. Chi square test was performed to see the association which showed a significant association between neuropathy development with nurses’ knowledge and practice as results were 0.000 (p-value is <0.005 taken as significant). Conclusions: There is a critical need to enhance oncology nurses' abilities in neurological assessment, and a reliable method of CIPN evaluation is essential. Guidelines for the treatment and evaluation of CIPN, as well as further studies in different health institutions to generalize the results across Pakistan, are urgently needed.

References

Asefa S, Aga F, Dinegde NG, Demie TG. Knowledge and practices on the safe handling of cytotoxic drugs among oncology nurses working at tertiary teaching hospitals in Addis Ababa, Ethiopia. Drug, Healthcare and Patient Safety. 2021 Mar; 13: 71-80. doi: 10.2147/DHPS.S289025.

Shamsi A, Azizzadeh Forouzi M, Iranmanesh S. Psychosocial risks among parents of children with cancer. Journal of Pediatric Nursing. 2016 Apr; 2(3): 44-55.

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. 2021 May; 71(3): 209-49. doi: 10.3322/caac.21660.

Sattar S, Alibhai SM, Fitch M, Krzyzanowska M, Leighl N, Puts MT. Chemotherapy and radiation treatment decision-making experiences of older adults with cancer: a qualitative study. Journal of Geriatric Oncology. 2018 Jan; 9(1): 47-52. doi: 10.1016/j.jgo.2017.07.013.

Mohammed HA, Kumait AS, Shakoor JA, Othman PN. Oncology Nursing Staff Knowledge and Practice Behaviors Toward Chemotherapy Impact on Peripheral Neuropathy: A Study from North of Iraq. Bahrain Medical Bulletin. 2021 Dec; 43(4): 715-719.

Falzone L, Salomone S, Libra M. Evolution of cancer pharmacological treatments at the turn of the third millennium. Frontiers in Pharmacology. 2018 Nov; 1300: 1-26. doi: 10.3389/fphar.2018.01300.

Ferlay J, Colombet M, Soerjomataram I, Parkin DM, Piñeros M, Znaor A, et al. Cancer statistics for the year 2020: An overview. International Journal of Cancer. 2021 Aug; 149(4): 778-89. doi: 10.1002/ijc.33588.

Gallegos R, Kogelman A, Wagner M, Cloud A, Olson M, Robideau K, et al. Chemotherapy Education: An interprofessional approach to standardizing processes and improving nurse and patient satisfaction. Clinical Journal of Oncology Nursing. 2019 Jun; 23(3): 309-14. doi: 10.1188/19.CJON.309-314.

Ali D, Naqvi SBS, Nasiri MI, Ahmed K, Zaheer K, Azeem M, et al. Evaluation of prevalence of different types of cancer and its chemotherapy in various ethnic groups of Pakistan: A retrospective study. Brazilian Journal of Pharmaceutical Sciences. 2020 Jun; 56: 1-8. doi: 10.1590/s2175-97902020000118915.

Zajaczkowska R, Kocot-Kepska M, Leppert W, Wrzosek A, Mika J, Wordliczek J. Mechanisms of Chemotherapy-Induced Peripheral Neuropathy. International Journal of Molecular Sciences. 2019 Mar; 20(6): 1451. doi: 10.3390/ijms20061451.

Binner M, Ross D, Browner I. Chemotherapy-induced peripheral neuropathy: assessment of oncology nurses' knowledge and practice. Oncology Nursing Forum. 2011 Jul; 38(4): 448-54. doi: 10.1188/11.ONF.448-454.

Staff NP, Grisold A, Grisold W, Windebank AJ. Chemotherapy‐induced peripheral neuropathy: a current review. Annals of neurology. 2017 Jun; 81(6): 772-81. doi: 10.1002/ana.24951.

Peters-Beijers T. Chemotherapy-induced peripheral neuropathy: an underestimated side effect with major impact on quality of life. [Doctoral Thesis, Maastricht University]. 2016 Dec. doi: 10.26481/dis.20161213tp.

Taverner T. Neuropathic pain: an overview. British Journal of Neuroscience Nursing. 2014 Sep; 20(9): 116-23. doi: 10.12968/bjnn.2014.10.3.116.

Dhawan S, Andrews R, Kumar L, Wadhwa S, Shukla G. A Randomized Controlled Trial to Assess the Effectiveness of Muscle Strengthening and Balancing Exercises on Chemotherapy-Induced Peripheral Neuropathic Pain and Quality of Life Among Cancer Patients. Cancer Nursing. 2020 Jul; 43(4): 269-80. doi: 10.1097/NCC.0000000000000693.

Pearce A, Haas M, Viney R, Pearson SA, Haywood P, Brown C, et al. Incidence and severity of self-reported chemotherapy side effects in routine care: A prospective cohort study. PLoS One. 2017 Oct; 12(10): e0184360. doi: 10.1371/journal.pone.0184360.

Bonetti L, Tolotti A, Anderson G, Nania T, Vignaduzzo C, Sari D, et al. Nursing interventions to promote patient engagement in cancer care: A systematic review. International Journal of Nursing Studies. 2022 May; 133: 104289. doi: 10.1016/j.ijnurstu.2022.104289.

Postma TJ and Heimans JJ. Grading of chemotherapy-induced peripheral neuropathy. Annals of Oncology. 2000 May;11(5):509-13. doi: 10.1023/A:1008345613594.

Qalawa SA. The Relationship between Oncology Nurses’ Practice behaviors, Knowledge and Confidence regarding Chemotherapy Induced Peripheral Neuropathy. Port Said Scientific Journal of Nursing. 2017 Jun; 4(1): 1-17. doi: 10.21608/pssjn.2017.33061.

Al-Atiyyat NM and Banifawaz AZ. Oncology nurses’ knowledge, practice, and confidence toward chemotherapy-induced peripheral neuropathy in Jordan. Saudi Medical Journal. 2018 Nov; 39(11): 1158. doi: 10.15537/smj.2018.11.23303.

Lisa Kottschade RN, Collins ML, Charlene Warton RN, Ghosh B. Nursing knowledge, practice patterns, and learning preferences regarding chemotherapy-induced peripheral neuropathy. InOncology Nursing Forum 2014 Nov 1 (Vol. 41, No. 6, p. 669). Oncology Nursing Society.