Comparing Dyslipidemia Patterns in Newly Diagnosed and Long-Term Type 2 Diabetics in a Tertiary Care Hospital at Mirpur Khas, Sindh: Dyslipidemia Patterns in Newly Diagnosed and Long-Term Type 2 Diabetics

Naveed Ahsan; Muhammad Anique; Rubina Shafi; Wajahat Ullah Khan; Shaista Alam; Fakhra Noureen

doi:10.54393/pjhs.v5i12.2225

Authors

Naveed Ahsan Department of Biochemistry, Bhitai Dental and Medical College, Mirpur Khas, Pakistan
Muhammad Anique Department of Pathology, Bhitai Dental and Medical College, Mirpur Khas, Pakistan
Rubina Shafi Department of Chemical Pathology, National University of Sciences and Technology, Islamabad, Pakistan
Wajahat Ullah Khan Department of Biochemistry, Mohi-Ud-Din Islamic Medical College, Mirpur, Pakistan
Shaista Alam Department of Microbiology/Pathology, Pak International Medical College Hayatabad, Peshawar, Pakistan
Fakhra Noureen Department of Chemical Pathology, Akhtar Saeed Medical College, Rawalpindi, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i12.2225

Keywords:

Type 2 Diabetes Mellitus, Dyslipidemia, Lipid Profile, Cardiovascular Risk

Abstract

Dyslipidemia is a common metabolic condition linked with type 2 diabetes mellitus and is a substantial risk factor for cardiovascular disease. The pathogenicity and pattern of dyslipidemia may vary with the duration of diabetes, requiring investigation of these changes to improve treatment approaches. Objectives: To compare the prevalence and patterns of dyslipidemia in newly diagnosed compared with long-term type 2 diabetes mellitus patients in a tertiary care hospital in Pakistan. Methods: A comparative cross-sectional study was conducted with 300 type 2 diabetes mellitus patients, divided into two groups: 150 newly diagnosed and 150 long-term diabetics. HbA1c and Lipid profiles (total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides) were assessed. Dyslipidemia was defined per American Diabetes Association guidelines. Statistical analysis was performed using SPSS version 25.0, with a p-value of <0.05 considered significant. Results: The results show that the patients with long-term type 2 diabetes mellitus are associated with significantly increased (92%, p<0.05) levels of lipid profile parameters as compared with the newly diagnosed type 2 diabetes mellitus patients (78%). Moreover, the mean HbA1c levels in blood are positively associated with the severity of dyslipidemia. Conclusion: It was concluded that dyslipidemia progressively increases with the advancement of type 2 diabetes mellitus.

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