Exploring the Metabolic Syndrome Trend in Young Adults in COVID-19 ERA

Metabolic Syndrome Trend in Young Adults

Authors

  • Zubia Aziz Department of Biochemistry, Liaquat College of Medicine and Dentistry, Karachi, Pakistan
  • Arisha Sohail Department of Biochemistry, Dow University of Health Sciences, Karachi, Pakistan
  • Madiha Soban Department of Biochemistry, Karachi Institute of Medical Sciences, Karachi, Pakistan
  • Syed Muhammad Huzaifah Shah Department of Medicine, Ziauddin University, Karachi, Pakistan
  • Fasiha Fatima Department of Biochemistry, Karachi Institute of Medical Sciences, Karachi, Pakistan
  • Zeba Haque Department of Biochemistry, Dow University of Health Sciences, Karachi, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i01.493

Keywords:

Young Adults, Obesity, Metabolic Syndrome, COVID-19

Abstract

COVID-19 pandemic imposed sudden changes in lifestyle with consequent altered metabolic status. Metabolic Syndrome is described as an altered metabolic profile of insulin resistance, dyslipidemia, hypertension, and central obesity which raises type 2 Diabetes Mellitus and cardiovascular disease danger at an early age. Objective: To analyze COVID-19 era status of obesity, hypertension, impaired glucose tolerance, dyslipidemia and metabolic syndrome in young adults. Methods: This was a cross-sectional study. 245 university students of either gender with ages 19–25 years were included. The lipid profile, fasting blood sugar and serum insulin was performed by kit method. The insulin resistance was determined by calculating the ratio of fasting glucose to insulin. SPSS version number 24.0 was used to analyze the data. Results:  Metabolic syndrome's prevalence in overweight and obese subjects was found to be 36%. The most prevalent risk factor of Metabolic syndrome was raised blood pressure (60%) followed by insulin resistance (57%) and dyslipidemia (40%). The positive coefficient correlations were found for all Metabolic syndrome risk factors in general except HDL. The multivariate regression analysis evidenced that the BMI and WHR were the significant predictors of Metabolic syndrome risk factors. Conclusion: The COVID-19 restrictions consequences call for an urgency to effectively address e metabolic and related problems, especially among young individuals.

References

Yanai H. Metabolic syndrome and COVID-19. Cardiology Research. 2020 Dec; 11(6): 360-365. doi: 10.14740/cr1181

Tune JD, Goodwill AG, Sassoon DJ, Mather KJ. Cardiovascular consequences of metabolic syndrome. Translational Research. 2017 May; 183: 57-70. doi: 10.1016/j.trsl.2017.01.001

Stierman B, Ogden CL, Yanovski JA, Martin CB, Sarafrazi N, Hales CM. Changes in adiposity among children and adolescents in the United States, 1999–2006 to 2011–2018. The American Journal of Clinical Nutrition. 2021 Oct; 114(4): 1495-504. doi: 10.1093/ajcn/nqab237

Malik MS, Malik M, Sukhera AB, Khalid MA, Waqas A, Qayyum W, et al. Metabolic syndrome and related inflammation, prevalence, and predictive value of c-reactive protein in south asian youths. Metabolic Syndrome and Related Disorders. 2021 Nov; 19(9): 483-90. doi: 10.1089/met.2021.0016

Tekalegn Y. Determinants of Overweight or Obesity among Men Aged 20–59 Years: A Case-Control Study Based on the 2016 Ethiopian Demographic and Health Survey. Journal of Obesity. 2021 Apr; 2021: 1-7. doi: 10.1155/2021/6627328

Breda J, Farrugia Sant'Angelo V, Duleva V, Galeone D, Heinen MM, Kelleher CC, et al. Mobilizing governments and society to combat obesity: Reflections on how data from the WHO European Childhood Obesity Surveillance Initiative are helping to drive policy progress. Obesity Reviews. 2021 Nov; 22(S6): e13217. doi: 10.1111/obr.13217

Dimitrova R, Fernandes D, Malik S, Suryani A, Musso P, Wiium N. The 7Cs and developmental assets models of positive youth development in India, Indonesia and Pakistan. InHandbook of Positive Youth Development. Springer, Cham. 2021: 17-33. doi: 10.1007/978-3-030-70262-5_2

Manca R, Bombillar F, Glomski C, Pica A. Obesity and immune system impairment: A global problem during the COVID-19 pandemic. International Journal of Risk & Safety in Medicine. 2022 Feb (Preprint): 1-6. doi: 10.3233/JRS-227007

Pérez-Rodrigo C, Gianzo Citores M, Hervás Bárbara G, Ruiz-Litago F, Casis Sáenz L, Arija V, et al. Patterns of change in dietary habits and physical activity during lockdown in Spain due to the COVID-19 pandemic. Nutrients. 2021 Jan; 13(2): 300. doi: 10.3390/nu13020300

Wang HH, Lee DK, Liu M, Portincasa P, Wang DQ. Novel insights into the pathogenesis and management of the metabolic syndrome. Pediatric Gastroenterology, Hepatology & Nutrition. 2020 May; 23(3): 189-230. doi: 10.5223/pghn.2020.23.3.189

Malik MS, Qayyum W, Farooq A, Waqas A, Sukhera AB, Khalid MA, et al. Dietary patterns, exercise, and the metabolic syndrome among young people in Urban Pakistan (Lahore). Metabolic Syndrome and Related Disorders. 2020 Feb; 18(1): 56-64. doi: 10.1089/met.2019.0021

Hao-Wei Xu MD, Hao Chen MD, Shu-Bao Zhang MD, Yu-Yang Yi MD, Xin-Yue Fang MD. Association Between Abdominal Obesity and Subsequent Vertebral Fracture Risk. Pain Physician. 2022 May; 25: E457-68.

Ulaganathan V, Kandiah M, Shariff ZM. A case-control study of the association between metabolic syndrome and colorectal cancer: a comparison of International Diabetes Federation, National Cholesterol Education Program Adults Treatment Panel III, and World Health Organization definitions. Journal of Gastrointestinal Oncology. 2018 Aug; 9(4): 650-663. doi: 10.21037/jgo.2018.04.01

Liu B, Li Y, Guo J, Fan Y, Li L, Li P. Body mass index and its change from adolescence to adulthood are closely related to the risk of adult metabolic syndrome in China. International Journal of Endocrinology. 2021 Feb; 2021: 1-7. doi: 10.1155/2021/8888862

Melamed OC, Selby P, Taylor VH. Mental Health and Obesity During the COVID-19 Pandemic. Current Obesity Reports. 2022 Mar; 11:1-9. doi: 10.1007/s13679-021-00466-6

Perona JS, Schmidt Rio‐Valle J, Ramírez‐Vélez R, Correa‐Rodríguez M, Fernández‐Aparicio Á, González‐Jiménez E. Waist circumference and abdominal volume index are the strongest anthropometric discriminators of metabolic syndrome in Spanish adolescents. European Journal of Clinical Investigation. 2019 Mar; 49(3): e13060. doi: 10.1111/eci.13060

Mili N, Paschou SA, Goulis DG, Dimopoulos MA, Lambrinoudaki I, Psaltopoulou T. Obesity, metabolic syndrome, and cancer: pathophysiological and therapeutic associations. Endocrine. 2021 Dec; 74(3): 478-97. doi: 10.1007/s12020-021-02884-x

Stefan N. Causes, consequences, and treatment of metabolically unhealthy fat distribution. The lancet Diabetes & Endocrinology. 2020 Jul; 8(7): 616-27. doi: 10.1016/S2213-8587(20)30110-8

White A, Liburd LC, Coronado F. Peer Reviewed: Addressing Racial and Ethnic Disparities in COVID-19 Among School-Aged Children: Are We Doing Enough?. Preventing Chronic Disease. 2021Jun; 18: 1-55. doi: 10.5888/pcd18.210084

Sathish T, Tapp RJ, Cooper ME, Zimmet P. Potential metabolic and inflammatory pathways between COVID-19 and new-onset diabetes. Diabetes and Metabolism. 2021 Mar; 47(2): 101204. doi: 10.1016/j.diabet.2020.10.002

Azizi F, Salehi P, Etemadi A, Zahedi-Asl S. Prevalence of metabolic syndrome in an urban population: Tehran Lipid and Glucose Study. Diabetes Research and Clinical Practice. 2003 Jul; 61(1): 29-37. doi: 10.1016/S0168-8227(03)00066-4

Tsenoli M, Smith JE, Khan MA. A community perspective of COVID-19 and obesity in children: causes and consequences. Obesity Medicine. 2021 Mar; 22: 100327. doi: 10.1016/j.obmed.2021.100327

Flaherty GT, Hession P, Liew CH, Lim BC, Leong TK, Lim V, et al. COVID-19 in adult patients with pre-existing chronic cardiac, respiratory and metabolic disease: a critical literature review with clinical recommendations. Tropical Diseases, Travel Medicine and Vaccines. 2020 Dec; 6(1): 1-3. doi: 10.1186/s40794-020-00118-y

Downloads

Published

2023-01-31
CITATION
DOI: 10.54393/pjhs.v4i01.493
Published: 2023-01-31

How to Cite

Aziz, Z. ., Sohail , A. ., Soban , M. ., Shah , S. M. H. ., Fatima, F. ., & Haque, Z. . (2023). Exploring the Metabolic Syndrome Trend in Young Adults in COVID-19 ERA: Metabolic Syndrome Trend in Young Adults. Pakistan Journal of Health Sciences, 4(01), 54–59. https://doi.org/10.54393/pjhs.v4i01.493

Issue

Section

Original Article

Plaudit

Most read articles by the same author(s)