Impact of Antioxidants in Preventing Dental Caries and Erosion
Antioxidants in Preventing Dental Caries and Erosion
DOI:
https://doi.org/10.54393/pjhs.v6i2.2199Keywords:
Dental Caries, Dental Erosion, Antioxidants, Green Tea ExtractAbstract
Dental erosion and caries are common oral health problems with serious consequences. Due to the increased intake of acidic foods and beverages, dental erosion is becoming more widely acknowledged as a serious oral health concern. Objectives: To assess the anti-oxidant (green tea extract, vitamin C, and vitamin E) efficaciousness in reducing dental caries and erosion. To look for changes in the scores for the DMFT (Decayed, Missing, and Filled teeth) and BEWE (Basic Erosive Wear Examination). Methods: A quasi-experimental study with groups (using green tea extract, vitamin C, and vitamin E, respectively) were formed from the 120 participants. BEWE, DMFT, and baseline demographics were noted. Salivary samples were examined for oxidative stress markers and antioxidant levels, and patients receiving certain treatments were assessed for changes in scores. A paired t-test was used to assess significance statistically. Results: All therapy groups showed significant declines in BEWE. DMFT scores slightly increased in all therapy groups as compared to the control group. The DMFT for Group A (vitamin C) increased from 4.2 ± 1.3 to 4.3 ± 1.1, Group B from 4.0 ± 1.4 to 4.0 ± 1.2, and Group C from 4.1 ± 1.2 to 4.2 ± 1.0, all with p-values of <0.001. The treatment groups saw almost similar BEWE scores as compared to the control group. Conclusion: It was concluded that antioxidants are helpful in the prevention of dental caries and erosion.
References
Pitts NB, Zero DT, Marsh PD, Ekstrand K, Weintraub JA, Ramos-Gomez F et al. Nature reviews Disease primers. 2017 May; 3(1): 1-6. doi: 10.1038/nrdp.2017.30.
Yanushevich OO, Maev IV, Krikheli NI, Andreev DN, Lyamina SV, Sokolov FS et al. Prevalence and risk of dental erosion in patients with gastroesophageal reflux disease: a meta-analysis. Dentistry journal. 2022 Jul; 10(7): 126. doi: 10.3390/dj10070126.
Tulek A, Mulic A, Runningen M, Lillemo J, Utheim TP, Khan Q et al. Genetic aspects of dental erosive wear and dental caries. International journal of dentistry. 2021; 2021(1): 5566733. doi: 10.1155/2021/5566733.
Achmad H, Armedina RN, Timokhina T, Goncharov VV, Sitanaya R, Riyanti E. Literature review: Problems of dental and oral health primary school children. Indian Journal of Forensic Medicine & Toxicology. 2021; 15(2). doi: 10.37506/ijfmt.v15i2.15019 .
Kanzow P, Wegehaupt FJ, Attin T, Wiegand A. Etiology and pathogenesis of dental erosion. Quintessence international. 2016 Apr; 47(4).
Konradsson K, Lingström PE, Emilson CG, Johannsen G, Ramberg P, Johannsen A. Stabilized stannous fluoride dentifrice in relation to dental caries, dental erosion and dentin hypersensitivity: A systematic review. American Journal of Dentistry. 2020 Apr; 33(2): 95-105.
de Sousa Né YG, Lima WF, Mendes PF, Baia-da-Silva DC, Bittencourt LO, Nascimento PC et al. Dental caries and salivary oxidative stress: global scientific research landscape. Antioxidants. 2023 Jan; 12(2): 330. doi: 10.3390/antiox12020330.
Subramanian AK, Narayan V, Navaneethan R. Oxidative Stress and Oral Diseases. Role of Oxidative Stress in Pathophysiology of Diseases. 2020: 1-2.
Loveren CV. Oral and dental health: prevention of dental caries, erosion, gingivitis and periodontitis. 2020 Jun. doi: 10.1007/978-981-15-1568-2_1.
de Souza-Rodrigues RD, Pereira WW, Lima RR. Antioxidants in Oral Cavity Disorders. In Drug Discovery and Design Using Natural Products. Cham: Springer Nature Switzerland. 2023 Aug: 453-463. doi: 10.1007/978-3-031-35205-8_16.
Gossweiler AG and Martinez-Mier EA. Vitamins and oral health. The Impact of Nutrition and Diet on Oral Health. 2020; 28: 59-67. doi: 10.1159/000455372.
de Oliveira AA, Xavier AL, da Silva TT, Debortolli AL, Ferdin AC, Boteon AP et al. Acquired pellicle engineering with the association of cystatin and vitamin E against enamel erosion. Journal of Dentistry. 2023 Nov; 138: 104680. doi: 10.1016/j.jdent.2023.104680.
Li Y, Jiang X, Hao J, Zhang Y, Huang R. Tea polyphenols: application in the control of oral microorganism infectious diseases. Archives of Oral Biology. 2019 Jun; 102: 74-82. doi: 10.1016/j.archoralbio.2019.03.027.
Hendi SS, Goodarzi MT, Moghimbeigi A, Ahmadi-Motamayel F. Evaluation of the status of salivary antioxidants in dental caries. Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders). 2020 Dec; 20(6): 816-21. doi: 10.2174/1871526519666191031100432.
de Sousa Né YG, Frazão DR, Bittencourt LO, Fagundes NC, Marañón-Vásquez G, Crespo-Lopez ME, Maia LC et al. Are dental caries associated with oxidative stress in saliva in children and adolescents? a systematic review. Metabolites. 2022 Sep; 12(9): 858. doi; 10.3390/metabo12090858.
Pytko-Polończyk J, Stawarz-Janeczek M, Kryczyk-Poprawa A, Muszyńska B. Antioxidant-rich natural raw materials in the prevention and treatment of selected oral cavity and periodontal diseases. Antioxidants. 2021 Nov; 10(11): 1848. doi: 10.3390/antiox10111848.
Lugo-Flores MA, Quintero-Cabello KP, Palafox-Rivera P, Silva-Espinoza BA, Cruz-Valenzuela MR, Ortega-Ramirez LA et al. Plant-derived substances with the antibacterial, antioxidant, and flavoring potential to formulate oral health care products. Biomedicines. 2021 Nov; 9(11): 1669. doi: 10.3390/biomedicines9111669.
Chen X, Daliri EB, Kim N, Kim JR, Yoo D, Oh DH. Microbial etiology and prevention of dental caries: exploiting natural products to inhibit cariogenic biofilms. Pathogens. 2020 Jul; 9(7): 569. doi: 10.3390/pathogens9070569.
Chatterjee S, Damle SG, Iyer N. A study on genetic and mutans streptococcal transmissibility of dental caries. Journal of Oral and Maxillofacial Pathology. 2022 Oct; 26(4): 604. doi: 10.4103/jomfp.jomfp_201_22.
Hegde MN, Kumari S, Hegde ND, Shetty SS. Relation between salivary and serum vitamin C levels and dental caries experience in adults-a biochemical study. Journal of Health and Allied Sciences Nitte University. 2013 Dec; 3(04): 030-3. doi: 10.1055/s-0040-1703698.
Blaner WS, Shmarakov IO, Traber MG. Vitamin A and vitamin E: will the real antioxidant please stand up? Annual review of nutrition. 2021 Oct; 41(1): 105-31. doi: 10.1146/annurev-nutr-082018-124228.
Sardari F, Khalili P, Rezvaninejad R, Rezvaninejad R, Eslami A. Dietary Vitamins and DMFT index in Rafsanjan adults, a Cross-sectional Study on Rafsanjan Adults Cohort Data. 2023 May. doi: 10.21203/rs.3.rs-2833239/v1.
Wortzman M and Nelson DB. A comprehensive topical antioxidant inhibits oxidative stress induced by blue light exposure and cigarette smoke in human skin tissue. Journal of Cosmetic Dermatology. 2021 Apr; 20(4): 1160-5. doi: 10.1111/jocd.13991.
Cagetti MG, Wolf TG, Tennert C, Camoni N, Lingström P, Campus G. The role of vitamins in oral health. A systematic review and meta-analysis. International journal of environmental research and public health. 2020 Feb; 17(3): 938. doi: 10.3390/ijerph17030938.
Jiang Q, Im S, Wagner JG, Hernandez ML, Peden DB. Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management. Free Radical Biology and Medicine. 2022 Jan; 178: 347-59.
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