Prevalence of Diabetic Retinopathy in Diabetic Subjects Visiting Diabetic Centers of Lahore, Pakistan

Prevalence of Diabetic Retinopathy in Diabetic Subjects

Authors

  • Saima Sharif Department of Zoology, Lahore College for Women University, Lahore, Pakistan
  • Farkhanda Manzoor Minhaj University, Lahore, Pakistan
  • Farah Khan Department of Zoology, Lahore College for Women University, Lahore, Pakistan
  • Shagufta Naz Department of Zoology, Lahore College for Women University, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i02.1299

Keywords:

Diabetic Retinopathy, Glycemic Control, Sedentary Lifestyle, Glycated Hemoglobin

Abstract

One of the chronic illnesses with the highest rate of growth in the globe and a major contributor to acquired visual loss is diabetes mellitus (DM). Globally, diabetic retinopathy (DR), a particular microvascular consequence of DM, continues to be the primary cause of acquired visual loss. Objective: To ascertain the percentage prevalence of diabetic retinopathy in diabetic subjects and the relationship between diabetic retinopathy and potential risk factors. Methods:  This study was conducted at Services Hospital, Lahore. The time duration of study was from November 2018 to June 2019. The patients were asked to fill a designed questionnaire which contained questions regarding patient’s demographic data, habits and history about the disease. Results: A total of 1000 diabetic patients were enrolled and among them 511 (51.1%) had diabetic retinopathy. Among 369 males, 173 (46.9%) males had diabetic retinopathy and among 631 females, 338 (53.6%) females had diabetic retinopathy. The mean age of studied population was 53.77±0.35 years. Logistic regression model indicated that age (years), gender, systolic blood pressure (mmHg), diastolic blood pressure (mmHg), HbA1c level (mmol/L), span of diabetes (years), family history of diabetes, sedentary lifestyle were the risk factors for incidence of diabetic retinopathy in this study. Conclusions: The occurrence of DR is high in the studied population. Age (years), span of diabetes (years), HbA1c level (mmol/L) and not doing exercise were seen to be exhibiting more important role towards the development of diabetic retinopathy.

References

Bastaki S. Diabetes mellitus and its treatment. International Journal of Diabetes and Metabolism. 2019; 13(3): 111-34. doi: 10.1159/000497580. DOI: https://doi.org/10.1159/000497580

Rother KI. Diabetes treatment—bridging the divide. The New England Journal of Medicine. 2007 Apr; 356(15): 1499. doi: 10.1056/NEJMp078030. DOI: https://doi.org/10.1056/NEJMp078030

Hotel R. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).2014.

Hu EA, Pan A, Malik V, Sun Q. White rice consumption and risk of type 2 diabetes: meta-analysis and systematic review. Bmj. 2012 Mar; 344. doi: 10.1136/bmj.e1454. DOI: https://doi.org/10.1136/bmj.e1454

Risérus U, Willett WC, Hu FB. Dietary fats and prevention of type 2 diabetes. Progress in Lipid Research. 2009 Jan; 48(1): 44-51. doi: 10.1016/j.plipres.2008.10.002. DOI: https://doi.org/10.1016/j.plipres.2008.10.002

Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. The Lancet. 2012 Jul; 380(9838): 219-29. doi: 10.1016/S0140-6736(12)61031-9. DOI: https://doi.org/10.1016/S0140-6736(12)61031-9

Henricsson M, Nyström L, Blohme G, Ostman J, Kullberg C, Svensson M et al. The incidence of retinopathy 10 years after diagnosis in young adult people with diabetes: results from the nationwide population-based Diabetes Incidence Study in Sweden (DISS). Diabetes Care. 2003 Feb; 26(2): 349-54. doi: 10.2337/diacare.26.2.349. DOI: https://doi.org/10.2337/diacare.26.2.349

International Diabetes Federation. Members [internet]. [Last Cited: 29th Feb 2024]. Available at: https://idf.org/our-network/regions-and-members/middle-east-and-north-africa/members/pakistan/.

Ahmed KR, Karim MN, Bukht MS, Bhowmik B, Acharyya A, Ali L et al. Risk factors of diabetic retinopathy in Bangladeshi type 2 diabetic patients. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2011 Oct; 5(4): 196-200. doi: 10.1016/j.dsx.2012.02.020. DOI: https://doi.org/10.1016/j.dsx.2012.02.020

Yau JW, Rogers SL, Kawasaki R, Lamoureux EL, Kowalski JW, Bek T et al. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012 Mar; 35(3): 556-64. doi: 10.2337/dc11-1909. DOI: https://doi.org/10.2337/dc11-1909

Stratton IM, Kohner EM, Aldington SJ, Turner RC, Holman RR, Manley SE et al. UKPDS 50: risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis. Diabetologia. 2001 Feb; 44: 156-63. doi: 10.1007/s001250051594. DOI: https://doi.org/10.1007/s001250051594

Tapp RJ, Shaw JE, Harper CA, De Courten MP, Balkau B, McCarty DJ et al. The prevalence of and factors associated with diabetic retinopathy in the Australian population. Diabetes Care. 2003 Jun; 26(6): 1731-7. doi: 10.2337/diacare.26.6.1731. DOI: https://doi.org/10.2337/diacare.26.6.1731

Ciulla TA, Amador AG, Zinman B. Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies. Diabetes Care. 2003 Sep; 26(9): 2653-64. doi: 10.2337/diacare.26.9.2653. DOI: https://doi.org/10.2337/diacare.26.9.2653

Jones S and Edwards RT. Diabetic retinopathy screening: a systematic review of the economic evidence. Diabetic Medicine. 2010 Mar; 27(3): 249-56. doi: 10.1111/j.1464-5491.2009.02870.x. DOI: https://doi.org/10.1111/j.1464-5491.2009.02870.x

Nguyen TT, Wang JJ, Sharrett AR, Islam FA, Klein R, Klein BE et al.Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care. 2008 Mar; 31(3): 544-9. doi: 10.2337/dc07-1528. DOI: https://doi.org/10.2337/dc07-1528

Mumtaz SN, Fahim MF, Arslan M, Shaikh SA, Kazi U, Memon MS. Prevalence of diabetic retinopathy in Pakistan; A systematic review. Pakistan Journal of Medical Sciences. 2018 Mar; 34(2): 493. doi: 10.12669/pjms.342.13819. DOI: https://doi.org/10.12669/pjms.342.13819

Ting DS, Cheung GC, Wong TY. Diabetic retinopathy: global prevalence, major risk factors, screening practices and public health challenges: a review. Clinical & experimental ophthalmology. 2016 May; 44(4): 260-77. doi: 10.1111/ceo.12696. DOI: https://doi.org/10.1111/ceo.12696

Hletala K, Harjutsalo V, Forsblom C, Summanen P, Groop PH, Flnndlane Study Group. Age at onset and the risk of proliferative retinopathy in type 1 diabetes. Diabetes Care. 2010 Jun; 33(6): 1315-9. doi: 10.2337/dc09-2278. DOI: https://doi.org/10.2337/dc09-2278

Rema M, Premkumar S, Anitha B, Deepa R, Pradeepa R, Mohan V. Prevalence of diabetic retinopathy in urban India: the Chennai Urban Rural Epidemiology Study (CURES) eye study, I. Investigative Ophthalmology & Visual science. 2005 Jul; 46(7): 2328-33. doi: 10.1167/iovs.05-0019. DOI: https://doi.org/10.1167/iovs.05-0019

Jaacks LM, Siegel KR, Gujral UP, Narayan KV. Type 2 diabetes: A 21st century epidemic. Best Practice & Research Clinical Endocrinology & Metabolism. 2016 Jun; 30(3): 331-43. doi: 10.1016/j.beem.2016.05.003. DOI: https://doi.org/10.1016/j.beem.2016.05.003

Downloads

Published

2024-02-29
CITATION
DOI: 10.54393/pjhs.v5i02.1299
Published: 2024-02-29

How to Cite

Sharif, S., Manzoor, F., Khan, F., & Naz, S. (2024). Prevalence of Diabetic Retinopathy in Diabetic Subjects Visiting Diabetic Centers of Lahore, Pakistan: Prevalence of Diabetic Retinopathy in Diabetic Subjects . Pakistan Journal of Health Sciences, 5(02), 65–69. https://doi.org/10.54393/pjhs.v5i02.1299

Issue

Section

Original Article

Plaudit