Comparison of Mean Retinal Nerve Fiber Layer Thickness on Optical Coherence Tomography (OCT) in Patients of Primary Open Angle Glaucoma (POAG) After Trabeculectomy vs Anti Glaucoma Medication: Retinal Nerve Fiber Layer Thickness

Sidra  Latif; Rashida  Riaz; Anjisha  Qamar; Misra  Anjum; Irfana  Bibi; Tahir  Shoukat; Humera  Zafar

doi:10.54393/pjhs.v4i05.699

Authors

Sidra Latif Department of Ophthalmology, Mayo Hospital, Lahore, Pakistan
Rashida Riaz Department of Ophthalmology, DHQ Hospital, Kasur, Pakistan
Anjisha Qamar Department of Ophthalmology, Gulab Devi Hospital, Lahore, Pakistan
Misra Anjum Department of Ophthalmology, The University of Lahore, Lahore, Pakistan
Irfana Bibi Department of Ophthalmology, Mayo Hospital, Lahore, Pakistan
Tahir Shoukat Department of Ophthalmology, The University of Lahore, Lahore, Pakistan
Humera Zafar Department of Ophthalmology, Mayo Hospital, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i05.699

Keywords:

Primary Open Angle Glaucoma, Optical Coherence Tomography (OCT), Retinal Nerve Fibre Layer Thickness, Trabeculectomy

Abstract

Trabeculotomy is a surgical procedure in which a fistula is created between anterior chamber and sub-conjunctival space for drainage of aqueous. Glaucoma is a chronic disease. Objective: To compare the mean retinal nerve fibre layer thickness in patients of primary open angle glaucoma after trabeculectomy versus anti glaucoma medication. Methods: This Randomized controlled study done in Institute of Ophthalmology, Eye Unit III, KEMU, Mayo Hospital, Lahore from 10^th Nov 2021 to 10^th May 2022. Non-Probability Convenient Sampling technique used for sample size calculation. 60 patients were selected fulfilling the inclusion and exclusion criteria. They were divided into two groups of 30 patients each. Group A patient were given topical anti-glaucoma treatment while Group B patients underwent trabeculectomy. Pre and three months post anti-glaucoma medication/trabeculectomy, OCT test was done and thickness of retinal nerve fibre layer documented. Results: In group A, mean post-treatment RNFL thickness was 0.076 ± 0.052 microns after three months of topical treatment. In group B, mean post-treatment RNFL thickness was 0.080 ± 0.0048 microns three months after trabeculectomy. Conclusions: Trabeculectomy increases the mean retinal nerve fibre layer thickness more than anti-glaucoma medication when measured on OCT.

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