Gingival Overgrowth In Patients Induced By Calcium Channel Blockers: Gingival Overgrowth and Calcium Channel Blockers

Muhammad Ali Panhwar; Javaid Unar; Iffat Panhwar; Tarique Hussain Shaikh; Seerat-Ul-Urooj Bhutto; Muhammad Amin Sehito; Rehmatullah Kandhro

doi:10.54393/pjhs.v5i06.1649

Authors

Muhammad Ali Panhwar Department of Community Dentistry, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
Javaid Unar Department of Community Dentistry, Dr. Ishrat-Ul-Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, Pakistan
Iffat Panhwar Department of Oral Maxillofacial Surgery, Dow University of Health Sciences, Karachi, Pakistan
Tarique Hussain Shaikh Department of Oral Maxillofacial Surgery, Isra University, Hyderabad, Pakistan
Seerat-Ul-Urooj Bhutto Department of Oral Pathology, Ibn-E-Sina University, Mirpurkhas, Pakistan
Muhammad Amin Sehito Department of Community Dentistry, Dr. Ishrat-Ul-Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, Pakistan
Rehmatullah Kandhro Department of Community Dentistry, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i06.1649

Keywords:

Cardiac Patients, Calcium Channel Blockers, Gingival Overgrowth, Amlodipine

Abstract

Gingival enlargement can be caused by a number of factors, including inflammatory conditions and the side effects of certain medications. Gingival overgrowth is one of the frequent features of gingival diseases. Objective: To find out frequency of calcium channel blockers causing gingival overgrowth. Methods: A descriptive cross-sectional study was conducted among cardiac patients visiting the cardiology department at Liaquat University Hospital, Hyderabad by convenience sampling technique for a time duration of six months. SPSS version 23.0, was used for data analysis. Chi-square test was applied with a significance level of P-value <0.05. Results: The most commonly used calcium channel blockers were amlodipine and diltiazem at 31.3% and 26.7% respectively, while 15.6% of cases were using nifedipine, 14.4% were on verapamil and 11.9% were on calcium channel blocker drug of bepridil. The severity of gingival overgrowth was significantly correlated with the male gender (p value= 0.001). Conclusions: After administration of calcium channel blockers, there is a potential that adverse consequences may occur such as gingival overgrowth, will become more common by prolong use of such drugs as indicated in this study.

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