Exploring the Antimicrobial Potential of Moringa Oleifera Extracts Against Acinetobacter Baumannii: Antimicrobial Potential of Moringa Oleifera Extracts Against Acinetobacter Baumannii

Saima Pervaiz; Afshan Zia; Nida Javed; Sara Masood Cheema; Umaira Ahsan; Ikram Ul Haq; Saba Shamim; Shah Jahan

doi:10.54393/pjhs.v6i3.1686

Authors

Saima Pervaiz Department of Immunology, University of Health Sciences, Lahore, Pakistan
Afshan Zia Department of Microbiology, University of Health Sciences, Lahore, Pakistan
Nida Javed Department of Pathology, Azra Naheed Medical College, Lahore, Pakistan
Sara Masood Cheema Department of Pathology, Azra Naheed Medical College, Lahore, Pakistan
Umaira Ahsan Department of Pathology, Abu Umara Medical and Dental College, Lahore, Pakistan
Ikram Ul Haq Department of Pathology, Sahara Medical College, Narowal, Pakistan
Saba Shamim Institute of Molecular Biology and Biotechnology, University of Lahore, Lahore, Pakistan
Shah Jahan Institute of Allied Health Sciences, University of Health Sciences, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v6i3.1686

Keywords:

Antimicrobial Activity, Pathogen, Plant Extract, Drug Resistance

Abstract

Background setups around the world, especially in Asian countries. Published data explained the situation of extreme drug resistance and left patients with very few antibiotic options against this particular pathogen. Plant and their extracts are well known for their antimicrobial properties. Moringa oleifera is one of the prime plants with multiple applications in industries, especially in health care. Objective: To determine the antimicrobial activity of Moringa oleifera plant extracts against Acinetobacter baumannii. Methods: In this experimental study, ethanol extracts of Moringa oleifera root, stem, and leaves were prepared and tested against Acinetobacter baumannii by the well diffusion method and minimum inhibitory concentration method. Four concentrations of all three extracts were prepared as 5mg/ml, 10mg/ml, 15mg/ml, and 20mg/ml. All experiments were tested three times. Results: No inhibition was seen at 5mg/ml, a 6mm zone diameter was observed at 10mg/ml, and 11mm was seen at 15mg/ml. Conclusions: It was concluded that Moringa oleifera showed good inhibition activity against Acinetobacter baumannii. This study does not include the quality analysis of extracts; after quality analysis and precise concentrations could create a huge opportunity in dealing with this extremely drug-resistant pathogen.

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