Factors Affecting On Dialysis Patients to Choose or Refuse Kidney Transplantation as Renal Replacement Therapy

Factors Affecting on Dialysis Patients

Authors

  • Azfar Ali Department of Urology & Kidney Transplantation, Post Graduate Medical Institute / Lahore General Hospital Lahore, Pakistan
  • Hasrat Khan Wifaq Department of Urology & Kidney Transplantation, Post Graduate Medical Institute / Lahore General Hospital Lahore, Pakistan
  • Aisha Tariq Alam Division of Pediatric Nephrology, King Edward Medical University/Mayo Hospital Lahore, Pakistan
  • Touqeer Aslam Waraich Department of Urology & Kidney Transplantation, Post Graduate Medical Institute / Lahore General Hospital Lahore, Pakistan
  • Usama Muhammad Kathia Department of Urology & Kidney Transplantation, Post Graduate Medical Institute / Lahore General Hospital Lahore, Pakistan
  • Muhammad Rizwan Gill Department of Urology & Kidney Transplantation, Post Graduate Medical Institute / Lahore General Hospital Lahore, Pakistan
  • Khizar Hayat Gondal Department of Urology & Kidney Transplantation, Post Graduate Medical Institute / Lahore General Hospital Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v4i03.526

Keywords:

Kidney Transplantation, Dialysis Patients, Factors Affecting

Abstract

Kidney transplantation (KT) is the most successful treatment for end-stage renal disease patients. But objective data about patients' willingness to undergo kidney transplant is still lacking in Pakistan. Objective: To assess barriers to KT and identify factors which could influence the willingness regarding KT among hemodialysis dependent patients.  Methods: This cross-sectional study carried out at Dialysis Unit, Dept. of Urology and Kidney transplantation Lahore General Hospital, Lahore on 100 hemodialysis dependent patients by completion of structured questionnaire about their knowledge and attitudes toward KT and how satisfied they were with dialysis. Results: The mean age of the patients was 42.8 ± 10.6 years with 55% male and 45% female patients. The percentage of patients who were willing to get a kidney transplant was 60%. The main reason of unwillingness to undergo KT was lack of donor (83.3%). Motivating factors in patients to choose KT were vascular access constraints 75%, studies or work difficulties 70%, fluid and dietary restrictions account for 63.3%. The percentage of patients who wanted a deceased kidney for transplant was 50%, whereas the percentage of patients who preferred a living kidney for transplant was 25% (17 % relatives and 8% non-relatives) and 25% of patients had no preference. Conclusion: Willingness to get kidney transplant is relatively low in Pakistan. Lack of donor, fear of surgery and financial problems are the main barriers for KT in ESRD patient

References

Nugent RA, Fathima SF, Feigl AB, Chyung D. The burden of chronic kidney disease on developing nations: a 21st century challenge in global health. Nephron Clinical Practice. 2011; 118(3): c269-77. doi: 10.1159/000321382

Dialysis in the Kingdom of Saudi Arabia. Saudi Journal of Kidney Diseases and Transplantation. 2019; 29: 1012-20

Anees M, Mumtaz A, Nazir M, Ibrahim M, Rizwan SM, Kausar T. Referral pattern fof hemodialysis patients to nephrologists. Journal of the College of Physicians and Surgeons--Pakistan: JCPSP. 2007 Nov; 17(11): 671-4

Cook C, Jorge A, Fu X, Niles J, Jeyabalan A, Zonozi R, et al. Association of renal transplantation with reduced risk of myocardial infarction and ischemic stroke in ANCA-associated vasculitis: An observational cohort study. Seminars in Arthritis and Rheumatism. 2021 Dec; 51(6): 1180-5. doi: 10.1016/j.semarthrit.2021.09.007

Knoll, GA. Kidney transplantation in the older adult. American Journal of Kidney Diseases, 2013. 61(5): 790-7. doi: 10.1053/j.ajkd.2012.08.049

Sarhan AL, Jarareh RH, Shraim M. Quality of life for kidney transplant recipients and hemodialysis patients in Palestine: a cross-sectional study. BMC Nephrology. 2021 Jun; 22(1). doi: 10.1186/s12882-021-02412-z

Jarl J, Desatnik P, Peetz Hansson U, Prütz KG, Gerdtham UG. Do kidney transplantations save money? A study using a before-after design and multiple register-based data from Sweden. Clinical Kidney Journal. 2018 Apr; 11(2): 283-8. doi: 10.1093/ckj/sfx088

Chironda G and Bhengu B. Perceptions of caregivers regarding engagement with integrated management of chronic kidney disease patients in selected public hospitals of KwaZulu-Natal region, South Africa. Health SA Gesondheid. 2018; 23(2018): 1-9. doi: 10.4102/hsag.v23i0.1104

Montalescot L, Dorard G, Speyer E, Legrand K, Ayav C, Combe C, et al. Patient perspectives on chronic kidney disease and decision-making about treatment. Discourse of participants in the French CKD-REIN cohort study. Journal of Nephrology. 2022 Jun; 35(5): 1387-97. doi: 10.1007/s40620-022-01345-6

Alansari H, Almalki A, Sadagah L, Alharthi M. Hemodialysis patients' willingness to undergo kidney transplantation: An observational study. InTransplantation Proceedings 2017 Nov; 49(9): 2025-30. doi: 10.1016/j.transproceed.2017.09.016

Boima V, Amissah-Arthur MB, Yorke E, Dey D, Fiagbe D, Yawson AE, et al. Determinants of willingness to accept kidney transplantation among chronic kidney disease patients in Ghana. BMC nephrology. 2021 Dec; 22: 1-2. doi: 10.1186/s12882-021-02335-9

Tan Q, Song T, Jiang Y, Qiu Y, Liu J, Huang Z, et al. Factors affecting willingness to receive a kidney transplant among hemodialysis patients in West China: A cross-sectional survey. Medicine. 2017 May; 96(18).e6722 doi: 10.1097/MD.0000000000006722

Qiao B, Liu L, Liu J, Xie J. A Study on the Attitude Toward Kidney Transplantation and Factors Among Hemodialysis Patients in China. Transplant Proceeding. 2016 Oct; 48(8): 2601-7. doi: 10.1016/j.transproceed.2016.06.060

Alobaidi S, Dwid N, Salem N, Mehdawi F, Kashgary A, Alhozali H, et al. Barriers to kidney transplantation among adults on maintenance dialysis in Western Region saudi arabia: A cross-sectional study. Saudi Journal of Kidney Diseases and Transplantation. 2021; 32(1): 49-59. doi: 10.4103/1319-2442.318548

Cockwell P and Fisher LA. The global burden of chronic kidney disease. Lancet. 2020; 395(10225): 662-664. doi: 10.1016/S0140-6736(19)32977-0

Romagnani P, Remuzzi G, Glassock R, Levin A, Jager KJ, Tonelli M, et al. Chronic kidney disease. Nature reviews Disease primers. 2017 Nov; 3(1): 1-24. doi: 10.1038/nrdp.2017.88

Bruns C, Giese J, Phillippi D, Moore D, Hall P. Knowledge and attitudes toward renal transplantation in individuals undergoing transplant evaluation. Progress in Transplantation. 2021 Sep; 31(3): 271-8. doi: 10.1177/15269248211024613

Kabbali N, Mikou S, El Bardai G, Tazi N, Ezziani M, Batta FZ, Arrayhani M, Houssaini TS. Attitude of hemodialysis patients toward renal transplantation: A Moroccan interregional survey. Transplantation proceedings. 2014 Jun; 46(5): 1328-31. doi: 10.1016/j.transproceed.2014.03.008

Ilori TO, Enofe N, Oommen A, Odewole O, Ojo A, Plantinga L, et al. Factors affecting willingness to receive a kidney transplant among minority patients at an urban safety-net hospital: a cross-sectional survey. BMC Nephrology. 2015; 16(1). doi: 10.1186/s12882-015-0186-2

Farah SS, Alhaji MM, Ahmed D, Alam S, Johan NH, Zulkipli IN, et al. Barriers to Kidney Transplantation as a Choice of Renal Replacement Therapy. Transplantation Proceeding. 2018 Dec; 50(10): 3165-71. doi: 10.1016/j.transproceed.2018.07.005

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Published

2023-03-31
CITATION
DOI: 10.54393/pjhs.v4i03.526
Published: 2023-03-31

How to Cite

Ali, A. ., Khan Wifaq, H. ., Tariq Alam, A. ., Aslam Waraich, T. ., Muhammad Kathia, U. ., Rizwan Gill, M. ., & Hayat Gondal, K. . (2023). Factors Affecting On Dialysis Patients to Choose or Refuse Kidney Transplantation as Renal Replacement Therapy: Factors Affecting on Dialysis Patients. Pakistan Journal of Health Sciences (Lahore), 4(03), 73–77. https://doi.org/10.54393/pjhs.v4i03.526

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