Patterns and Outcomes of Adult Cardiac Surgery in a Tertiary Hospital in Pakistan: A Seven-Year Single-Surgeon Retrospective Study
Patterns and Outcomes of Adult Cardiac Surgery
DOI:
https://doi.org/10.54393/pjhs.v7i2.3544Keywords:
Coronary Artery Bypass Grafting, Valvular Heart Disease, Rheumatic Heart Disease, Developing CountryAbstract
Cardiovascular disease is a major health burden in Pakistan, where access to cardiac surgery is limited. Understanding disease patterns and cardiac surgical procedures in high-burden societies can guide resource allocation to improve patient outcomes. Objectives: To evaluate retrospectively the pattern of adult cardiac surgical procedures and their outcomes performed by a single surgeon at a tertiary hospital in Pakistan. Methods: This retrospective observational study included 1,404 consecutive adult patients operated on by a single surgeon at CPEIC, Multan. Data were collected from all consecutive adult patients (≥15 years), of either sex, who underwent surgery by a single cardiac surgeon between May 2018 and July 2025. The data were obtained from a prospectively maintained surgeon's database. Fisher’s exact test was used for small group comparisons. Results: A total of 1,404 patients underwent cardiac surgery. Coronary artery bypass grafting comprised 70.0% (on‑pump 55.9%, off‑pump 11.3%), valvular surgery 21.6%, congenital repairs 2.3%, aortic root 1.0%, and post-MI VSR repair 1.5%. In isolated CABG, the internal mammary artery was used in 92.4%, with a mean of 2.96 ± 0.93 grafts. Complications occurred in 20.4%. Early mortality was 3.1%, with the lowest rates in CABG (1.9%) and the highest in VSR repair (23.8%). Ventilation time and hospital stay were significantly longer in aortic root and redo procedures (p<0.05). Conclusions: Over seven years, CABG and valvular procedures predominated, with overall mortality and complication rates comparable to regional benchmarks. On-pump CABG provided more complete revascularization, while complex surgeries carried a higher risk.
References
Lindstrom M, DeCleene N, Dorsey H, Fuster V, Johnson CO, LeGrand KE et al. Global Burden of Cardiovascular Diseases and Risks Collaboration, 1990-2021. Journal of the American College of Cardiology. 2022 Dec; 80(25): 2372-425. doi: 10.1016/j.jacc.2022.11.001. DOI: https://doi.org/10.1016/j.jacc.2022.11.001
World Health Organization. Cardiovascular diseases (CVDs) [Internet]. Geneva: WHO. 2025 Jul. [Last accessed on 17 Nov 2025]. https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds).
World Health Organization. World Health Statistics 2025: Monitoring Health for the SDGS, Sustainable Development Goals. 2025 May. https://www.who.int/publications/i/item/9789240110496.
Lamichhane P, Pokhrel KM, Pokharel P, Bhandari B, Lamichhane P, Regmi PR. Prevalence of Rheumatic Heart Disease in South Asia: A Systematic Review and Meta-Analysis. International Journal of Cardiology. 2022 Jul; 358: 110-9. doi: 10.1016/j.ijcard.2022.04.010. DOI: https://doi.org/10.1016/j.ijcard.2022.04.010
Hasnain M, Yasin S, Khan FR, Aslam K, Ihsan A, Farooq N. Prevalence and Risk Factors of Coronary Artery Disease in Pakistan: A Multicenter Cohort Study. Journal of Population Therapeutics and Clinical Pharmacology. 2024; 31(1): 2956-64. doi: 10.53555/hnwhqk98. DOI: https://doi.org/10.53555/hnwhqk98
Devkota S, Dhungana RR, Pandey AR, Poudel CM, Shrestha H, Bhattarai A. Risk Factors of Coronary Artery Disease: A Hospital-Based Study. Journal of Nepal Health Research Council. 2022; 20(02): 487-493.
Jamali YA, Kazi S, Chandio MN, Nabeel SK, Kanhar AA, Riaz U et al. Prevalence and Risk Factors of Coronary Heart Disease in Nawabshah: A Case-Control Study: Prevalence and Risk Factors of Coronary Heart Disease. Pakistan Journal of Health Sciences. 2024 Oct: 194-8. doi: 10.54393/pjhs.v5i10.2102. DOI: https://doi.org/10.54393/pjhs.v5i10.2102
Hosain N. The Early Days of Cardiac Surgery in South Asia: The History and Heritage. The Annals of Thoracic Surgery. 2017 Jul; 104(1): 361-6. doi: 10.1016/j.athoracsur.2017.01.039. DOI: https://doi.org/10.1016/j.athoracsur.2017.01.039
National Institute of Cardiovascular Diseases (NICVD). History. 2025; 2(1).
Vervoort D, Meuris B, Meyns B, Verbrugghe P. Global Cardiac Surgery: Access to Cardiac Surgical Care Around the World. The Journal of Thoracic and Cardiovascular Surgery. 2020 Mar; 159(3): 987-96. doi: 10.1016/j.jtcvs.2019.04.039. DOI: https://doi.org/10.1016/j.jtcvs.2019.04.039
Jan A, Hayat MK, Khan MA, Ullah R. Trends in Perioperative Parameters and Postoperative Complications Associated with Coronary Artery Bypass Graft Surgery (CABG); A Four-Year Retrospective Study. Pakistan Journal of Medical Sciences. 2021 Nov; 37(7): 1734. doi: 10.12669/pjms.37.7.4315. DOI: https://doi.org/10.12669/pjms.37.7.4315
Wang J, Gu C, Yu W, Gao M, Yu Y. Short-and Long-Term Patient Outcomes from Combined Coronary Endarterectomy and Coronary Artery Bypass Grafting: A Meta-Analysis of 63,730 Patients (PRISMA). Medicine. 2015 Oct; 94(41): e1781. doi: 10.1097/MD.0000000000001781. DOI: https://doi.org/10.1097/MD.0000000000001781
Hill JM, Kereiakes DJ, Shlofmitz RA, Klein AJ, Riley RF, Price MJ et al. Intravascular Lithotripsy for Treatment of Severely Calcified Coronary Artery Disease. Journal of the American College of Cardiology. 2020 Dec; 76(22): 2635-46. doi: 10.1016/j.jacc.2020.09.603. DOI: https://doi.org/10.1016/j.jacc.2020.09.603
Wang C, Chen J, Gu C, Li J. Analysis of Survival After Coronary Endarterectomy Combined with Coronary Artery Bypass Grafting Compared with Isolated Coronary Artery Bypass Grafting: A Meta-Analysis. Interactive Cardiovascular and Thoracic Surgery. 2019 Sep; 29(3): 393-401. doi: 10.1093/icvts/ivz125. DOI: https://doi.org/10.1093/icvts/ivz125
Inam H, Sohail AA, Aamir A, Ahmed KS, Asif N, Sharfuddin SS. Coronary Artery Bypass Grafting in Young Adults. History. 2024 Dec; 14: 10-45.
Matteucci M, Ronco D, Corazzari C, Fina D, Jiritano F, Meani P et al. Surgical Repair of Postinfarction Ventricular Septal Rupture: Systematic Review and Meta-Analysis. The Annals of Thoracic Surgery. 2021 Jul; 112(1): 326-37. doi: 10.1016/j.athoracsur.2020.08.050. DOI: https://doi.org/10.1016/j.athoracsur.2020.08.050
Hannan EL, Wu C, Smith CR, Higgins RS, Carlson RE, Culliford AT et al. Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery: Differences in Short-Term Outcomes and Long-Term Mortality and Need for Subsequent Revascularization. Circulation. 2007 Sep; 116(10): 1145-52. doi: 10.1161/CIRCULATIONAHA.106.675595. DOI: https://doi.org/10.1161/CIRCULATIONAHA.106.675595
Zia K, Mangi AR, Bughio H, Tariq K, Chaudry PA, Karim M. Initial Experience of Minimally Invasive Concomitant Aortic and Mitral Valve Replacement/Repair at a Tertiary Care Cardiac Centre of a Developing Country. Cureus. 2019 Sep; 11(9). doi: 10.7759/cureus.5707. DOI: https://doi.org/10.7759/cureus.5707
Kytö V, Myllykangas ME, Sipilä J, Niiranen TJ, Rautava P, Gunn J. Long-Term Outcomes of Mechanical vs Biologic Aortic Valve Prosthesis in Patients Older Than 70 Years. The Annals of Thoracic Surgery. 2019 Nov; 108(5): 1354-60. doi: 10.1016/j.athoracsur.2019.04.012. DOI: https://doi.org/10.1016/j.athoracsur.2019.04.012
Perazzo A, Steffen SP, Gaiotto FA, Santos RH, Jatene FB, Lorusso R. A Milestone in Cardiac Care: The Intra-Aortic Balloon Pump in Cardiac Surgery and Transplantation. Brazilian Journal of Cardiovascular Surgery. 2024 Jun; 39(2): e20240991. doi: 10.21470/1678-9741-2024-0991. DOI: https://doi.org/10.21470/1678-9741-2024-0991
Wang Q, Tao Y, Zhang X, Xu S, Peng Y, Lin L et al. The Incidence, Risk Factors, and Hospital Mortality of Prolonged Mechanical Ventilation among Cardiac Surgery Patients: A Systematic Review and Meta-Analysis. Reviews in Cardiovascular Medicine. 2024 Nov; 25(11): 409. doi: 10.31083/j.rcm2511409. DOI: https://doi.org/10.31083/j.rcm2511409
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Pakistan Journal of Health Sciences

This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments



