Post Operative Outcomes of Acute Perforated Appendix During Index Admission
Acute Perforated Appendix During Index Admission
DOI:
https://doi.org/10.54393/pjhs.v6i12.3423Keywords:
Acute Appendicitis, Appendicular Perforation, Postoperative OutcomesAbstract
Acute perforated appendicitis is a serious condition associated with higher morbidity, prolonged hospital stays, and increased risk of complications. Understanding postoperative outcomes is crucial for optimizing patient care, improving clinical decision-making, and reducing healthcare burdens. Objective: To determine the postoperative outcomes of acute perforated appendicitis during index hospital admission. Methods: This descriptive study was conducted at the Department of Surgery, Khyber Teaching Hospital, Peshawar, from October 1, 2024, to July 31, 2025. Male and female patients aged 18 to 60 years diagnosed with acute perforated appendicitis were enrolled. The patients were evaluated for postoperative outcomes, recorded in terms of surgical site infection, wound dehiscence, hospital stay, and intestinal obstruction. Data analysis was carried out using SPSS version 26.0. Results: The Mean age of the participants was 33.91 ± 11.834 years, while the mean hospital stay was 7.12 ± 2.721 days. Most of the patients were male (n=101, 67.8%). Retrocecal position of the appendix was frequently recorded in 98 patients (65.8%). Hospital stay more than seven days was observed in 57 patients (38.3%), followed by surgical site infection (n=47, 31.5%). Wound dehiscence was the least frequently recorded in 21 patients (14.1%). Conclusions: Acute perforated appendicitis was associated with increased occurrence of postoperative complications and morbidities. Male patients with advanced age were more likely to experience prolonged hospital stay and surgical site infection.
References
Qurashi FA, Keegan AC, D’Adamo CR, Wolf JH. Post-Operative Day Zero Discharge After Laparoscopic Appendectomy Does Not Worsen High-Yield Outcomes: A NSQIP Database Observational Study. Journal of Investigative Surgery. 2022 Oct; 35(10): 1767-71. doi: 10.1080/08941939.2022.2119493.
Khan MS, Siddiqui MT, Shahzad N, Haider A, Chaudhry MB, Alvi R. Factors Associated with Complicated Appendicitis: View from A Low-Middle Income Country. Cureus. 2019 May; 11(5). doi: 10.7759/cureus.4765.
Bancke Laverde BL, Maak M, Langheinrich M, Kersting S, Denz A, Krautz C et al. Risk Factors for Postoperative Morbidity, Prolonged Length of Stay, and Hospital Readmission After Appendectomy for Acute Appendicitis. European Journal of Trauma and Emergency Surgery. 2023 Jun; 49(3): 1355-66. doi: 10.1007/s00068-023-02225-9.
Sohail AH, Hakmi H, Cohen K, Hurwitz JC, Brite J, Cimaroli S et al. Predictors of in-Hospital Appendiceal Perforation in Patients with Non-Perforated Acute Appendicitis with Appendicolithiasis at Presentation. BioMed Central Surgery. 2023 Oct; 23(1): 317. doi: 10.1186/s12893-023-02210-4.
Zewdu D, Wondwosen M, Tantu T, Tilahun T, Teshome T, Hamu A. Predictors and Management Outcomes of Perforated Appendicitis in Sub-Saharan African Countries: A Retrospective Cohort Study. Annals of Medicine and Surgery. 2022 Aug; 80: 104194. doi: 10.1016/j.amsu.2022.104194.
Rai A, Huda F, Kumar P, David LE, Basu S, Singh S. Predictors of Postoperative Outcome in Emergency Laparotomy for Perforation Peritonitis: A Retrospective Cross-Sectional Study. Archives of Academic Emergency Medicine. 2022 Oct; 10(1): e86.
Afenigus AD, Bayieh AM, Kassahun B. Treatment Outcomes of Acute Appendicitis and Associated Factors Among Admitted Patients with A Diagnosis of Acute Abdomen in Debre Markos Referral Hospital, Amhara Region, North West Ethiopia. Journal of Perioperative Practice. 2022 May; 32(5): 123-30. doi: 10.1177/1750458920928473.
Kupietzky A, Gross M, Dover R, Maden A, Parnasa SY, Shussman N et al. Operative Outcomes of Patients with Recurrent Uncomplicated Appendicitis are Similar to Patients with Acute Uncomplicated Appendicitis. Journal of Surgical Research. 2025 Apr; 308: 209-15. doi: 10.1016/j.jss.2025.02.034.
Martinez-Perez A, Paya-Llorente C, Santarrufina-Martinez S, Sebastián-Tomás JC, Martinez-Lopez E, de’Angelis N. Predictors for Prolonged Length of Stay After Laparoscopic Appendectomy for Complicated Acute Appendicitis in Adults. Surgical Endoscopy. 2021 Jul; 35(7): 3628-35. doi: 10.1007/s00464-020-07841-9.
Potey K, Kandi A, Jadhav S, Gowda V. Study of Outcomes of Perforated Appendicitis in Adults: A Prospective Cohort Study. Annals of Medicine and Surgery. 2023 Apr 1;85(4):694-700. doi: 10.1097/MS9.0000000000000277.
Pramod T and Prakashkumar MN. Surgical Outcome in Patients with Complicated Appendicitis Treated at A Medical College Hospital. International Journal of Surgery. 2019 Jun; 6: 2379-85. doi: 10.18203/2349-2902.isj20192959.
Madeka I, Patel K, Altshuler P, Iyer A, Dukle S, Kohli A. Clinical Outcomes in Patients with Complicated Appendicitis. Surgical Endoscopy. 2024 Jan; 38(1): 384-9. doi: 10.1007/s00464-023-10503-1.
Takirambudde S, Ruffolo LI, Wakeman DS, Dale BS, Arca MJ, Wilson NA. Social Determinants of Health Are Associated with Postoperative Outcomes in Children with Complicated Appendicitis. Journal of Surgical Research. 2022 Nov; 279: 692-701. doi: 10.1016/j.jss.2022.06.059.
Khalid B, Malik I, Khan Z, Farooq U, Shehzad M, Ullah M. Frequency of Perforated Appendix in Patients Presenting with Acute Appendicitis in Surgical C Ward, Ayub Teaching Hospital. Indus Journal of Bioscience Research. 2025 May; 3(5): 843-7. doi: 10.70749/ijbr.v3i5.1546.
Hsiao R, Youngson E, Lafontaine A, Fathimani K, Williams DC. Comparison of Outcomes After Appendectomy in First Nations and Non–First Nations Patients in Northern Alberta. Canadian Journal of Surgery. 2023 Nov; 66(6): E540. doi: 10.1503/cjs.011222.
Zhang A, Lu H, Chen F, Wu Y, Luo L, Sun S. Systematic Review and Meta-Analysis of the Effects of the Perioperative Enhanced Recovery After Surgery Concept on the Surgical Treatment of Acute Appendicitis in Children. Translational Pediatrics. 2021 Nov; 10(11): 3034. doi: 10.21037/tp-21-457.
Uttinger K, Baum P, Diers J, Seehofer D, Germer CT, Wiegering A. The Impact of Surgical Timing on Outcome in Acute Appendicitis in Adults: A Retrospective Observational Population-Based Cohort Study. International Journal of Surgery. 2024 Aug; 110(8): 4850-8. doi: 10.1097/JS9.0000000000001528.
Islam N, Thakkar G, Ferguson C, Kennedy K, Bennett N, Oyetunji T et al. Impact of an Acute Care Surgery Clinical Pathway on Patient Outcomes in Acute Appendicitis. Surgical infections. 2025 Jan; 26(1): 11-6. doi: 10.1089/sur.2024.100.
Leandri M, Vallicelli C, Santandrea G, Perrina D, Bravi F, Sartelli M et al. Postoperative Infections After Appendectomy for Acute Appendicitis: The Surgeon’s Checklist. Antibiotics. 2025 Sep; 14(9): 954. doi: 10.3390/antibiotics14090954.
Cironi K, Albuck AL, McLafferty B, Mortemore AK, McCarthy C, Hussein M et al. Risk Factors for Postoperative Infections Following Appendectomy of Complicated Appendicitis: A Meta-analysis and Retrospective Single-institutional Study. Surgical Laparoscopy Endoscopy and Percutaneous Techniques. 2024 Feb; 34(1): 20-8. doi: 10.1097/SLE.0000000000001234.
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