Exposure of Acute Gastroenteritis in Relation to Season: A Cross-Sectional Study Based on Demographic Representation of Paediatric Patients with Their Outcomes
Acute Gastroenteritis in Relation to Season: Demographic Representation of Paediatric Patients
DOI:
https://doi.org/10.54393/pjhs.v6i12.3267Keywords:
Acute Gastroenteritis, Paediatrics, Seasonal Variation, Demographic RepresentationAbstract
Among children, acute gastroenteritis (viral) is a major concern for public health. In Pakistan, childhood mortality remains fourth largest, with gastrointestinal infections remaining a major cause. Objectives: To compare acute gastroenteritis and seasonal variations based on their demographic representation. Methods: After informed consent and ethical approval, this cross-sectional (prospective) research was carried out in the Paediatric Ward of Al-Tibri Medical College and Hospital, Karachi, from June 2023 to May 2024. Patients diagnosed with acute gastroenteritis were included, while those with any other diagnosis (such as intestinal obstruction, urinary tract infection, etc.) were excluded. SPSS version 23.0 was used for the analysis of data. To test significance, the chi-square test was applied at a p-value≤0.05. Results: Among 377 paediatric cases, 55% were male and 45% female, with 34% infants and 38% between 1-4 years. 63% of patients were admitted in the summer and 37% in winter, with most being admitted in May 2024 (14%) and least in the month of November 2023 (3%). The majority were discharged alive and healthy (99%). A significant association was observed in patients admitted in each month (p-value<0.001). Conclusions: This study showed that acute gastroenteritis in paediatric patients was more common among males and children aged 1–4 years, with a significantly higher number of admissions during the summer months, particularly in May 2024. Despite the seasonal surge, almost all patients recovered well, with 99% discharged alive and healthy.
References
Zhou J, Sun Y. Effect of COVID-19 Protective Measures on the Epidemiology Characteristics of Rotavirus, Adenovirus, and Coinfections Among Pediatric Patients with Acute Gastroenteritis in Hangzhou, China. Microbiology Spectrum. 2024 Mar; 12(3): e04007-23. doi: 10.1128/spectrum.04007-23.
Orhan Ö and Bulut M. Evaluation of Pediatric Patients Installed Due to Acute Gastroenteritis. The European Research Journal. 2023 Nov; 9(6): 1392-7. doi: 10.18621/eurj.1261344.
Yassin BA, Ali SH, Abu Al-ess HQ, Mohammed KI, Al-Timimi MF, Al-Janabi MK et al. A Trend of Seasonality of Enteric Adenoviral Gastroenteritis in Pediatric Patients Less Than Five Years from Baghdad. Journal of Research in Medical and Dental Science. 2018 Jul; 6(4): 18-23.
Jin HI, Lee YM, Choi YJ, Jeong SJ. Recent Viral Pathogen in Acute Gastroenteritis: A Retrospective Study at A Tertiary Hospital for 1 Year. Korean Journal of Pediatrics. 2016 Mar; 59(3): 120. doi: 10.3345/kjp.2016.59.3.120.
Haddadin Z, Batarseh E, Hamdan L, Stewart LS, Piya B, Rahman H et al. Characteristics of GII. 4 Norovirus Versus Other Genotypes in Sporadic Pediatric Infections in Davidson County, Tennessee, USA. Clinical Infectious Diseases. 2021 Oct; 73(7): e1525-31. doi: 10.1093/cid/ciaa1001.
Rojjanadumrongkul K, Kumthip K, Khamrin P, Ukarapol N, Ushijima H, Maneekarn N. Enterovirus Infections in Pediatric Patients Hospitalized with Acute Gastroenteritis in Chiang Mai, Thailand, 2015–2018. PeerJ. 2020 Aug; 8: e9645. doi: 10.7717/peerj.9645.
Florez ID, Nino-Serna LF, Beltran-Arroyave CP. Acute Infectious Diarrhea and Gastroenteritis in Children. Current Infectious Disease Reports. 2020 Feb; 22(2): 4. doi: 10.1007/s11908-020-0713-6.
Dhage VD and Nagtode N. Health Problems among Under-Five Age Group Children in Developing Countries: A Narrative Review. Cureus. 2024 Feb; 16(2). doi: 10.7759/cureus.55019.
Flynn TG, Olortegui MP, Kosek MN. Viral Gastroenteritis. The Lancet. 2024 Mar; 403(10429): 862-76. doi: 10.1016/S0140-6736(23)02037-8.
Guarino A, Aguilar J, Berkley J, Broekaert I, Vazquez‐Frias R, Holtz L et al. Acute Gastroenteritis in Children of the World: What Needs to Be Done? Journal Of Pediatric Gastroenterology and Nutrition. 2020 May; 70(5): 694-701. doi: 10.1097/MPG.0000000000002669.
Afshan K, Narjis G, Qureshi IZ, Cappello M. Social Determinants and Causes of Child Mortality in Pakistan: Analysis of National Demographic Health Surveys from 1990 To 2013. Journal of Pediatrics and Child Health. 2020 Mar; 56(3): 457-72. doi: 10.1111/jpc.14670.
Amodio E, De Grazia S, Genovese D, Bonura F, Filizzolo C, Collura A et al. Clinical and Epidemiologic Features of Viral Gastroenteritis in Hospitalized Children: An 11-Year Surveillance in Palermo (Sicily). Viruses. 2022 Dec; 15(1): 41. doi: 10.3390/v15010041.
Pranesh PT, Singh CD, Sivanandam A, Muthusamy R, Sharma S, Alqahtani T et al. Predictive Analysis of Pediatric Gastroenteritis Risk Factors and Seasonal Variations Using VGG Dense Hybrid-Net-Classifier, A Novel Deep Learning Approach. Scientific Reports. 2025 Jul; 15(1): 23912. doi: 10.1038/s41598-025-08718-4.
Giri S, Kumar CG, Khakha SA, Chawla-Sarkar M, Gopalkrishna V, Chitambar SD et al. Diversity of Rotavirus Genotypes Circulating in Children < 5 Years of Age Hospitalized for Acute Gastroenteritis in India from 2005 to 2016: Analysis of Temporal and Regional Genotype Variation. BioMed Central Infectious Diseases. 2020 Oct; 20(1): 740.
Chong KC, Chan EY, Lee TC, Kwok KL, Lau SY, Wang P et al. A 21-Year Retrospective Analysis of Environmental Impacts on Pediatric Acute Gastroenteritis in an Affluent Setting. Science of The Total Environment. 2021 Apr; 764: 142845. doi: 10.1016/j.scitotenv.2020.142845
Chao DL, Roose A, Roh M, Kotloff KL, Proctor JL. The Seasonality of Diarrheal Pathogens: A Retrospective Study of Seven Sites Over Three Years. PLOS Neglected Tropical Diseases. 2019 Aug; 13(8): e0007211. doi: 10.1371/journal.pntd.0007211.
Mero S, Lääveri T, Ursing J, Rombo L, Kofoed PE, Kantele A. Seasonal Variation of Diarrhoeal Pathogens Among Guinea-Bissauan Children Under Five Years of Age. PLOS Neglected Tropical Diseases. 2023 Mar; 17(3): e0011179. doi: 10.1371/journal.pntd.0011179.
Salami A, Fakih H, Chakkour M, Salloum L, Bahmad HF, Ghssein G. Prevalence, Risk Factors and Seasonal Variations of Different Enteropathogens in Lebanese Hospitalized Children with Acute Gastroenteritis. BMC Pediatrics. 2019 Apr; 19(1): 137. doi: 10.1186/s12887-019-1513-8.
Stanyevic B, Sepich M, Biondi S, Baroncelli GI, Peroni D, Di Cicco M. The Evolving Epidemiology of Acute Gastroenteritis in Hospitalized Children in Italy. European Journal of Pediatrics. 2022 Jan; 181(1): 349-58. doi: 10.1007/s00431-021-04210-z.
Li F, Guo L, Li Q, Xu H, Fu Y, Huang L et al. Changes in the Epidemiology and Clinical Characteristics of Viral Gastroenteritis among Hospitalized Children in the Mainland of China: A Retrospective Study from 2016 to 2020. BioMed Central Pediatrics. 2024 May; 24(1): 303. doi: 10.1186/s12887-024-04776-1.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Pakistan Journal of Health Sciences

This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments



