Assessment of Deranged Lipid Profiles and Correlated Dependent Factors in Patients with Ischemic Stroke at a Tertiary Care Setup in Islamabad: Assessment of Deranged Lipid Profiles and Dependent Factors in Patients

Adnan Ghafoor; Abdur Rehman; Maria Sarfaraz; Salim Badshah; Daud Ahmad Jan; Noor Hayat

doi:10.54393/pjhs.v6i1.1975

Authors

Adnan Ghafoor Fauji Foundation Hospital, Rawalpindi, Pakistan
Abdur Rehman Fauji Foundation Hospital, Rawalpindi, Pakistan
Maria Sarfaraz Rawal Institute of Health Sciences, Islamabad, Pakistan
Salim Badshah Health Department, Khyber Pakhtunkhwa, Pakistan
Daud Ahmad Jan Lady Reading Hospital, Peshawar, Pakistan
Noor Hayat Department of ENT, Medical Teaching Institution, Mardan Medical Complex, Mardan, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v6i1.1975

Keywords:

Cerebrovascular, Dyslipidemia, Ischemic stroke, Lipid Profiles, Assessment

Abstract

The deranged lipid profile of patients is greatly associated with multiple complications hence leading towards the co morbidities and eventually been a reason of high mortalities. Objectives: To determine the cases of deranged lipid profiles among patients with confirmed diagnosis of ischemic stroke, dependent variables & co morbidities. Methods: A Descriptive, cross-sectional study was conducted at the Department of Medicine Fauji Foundation Hospital Rawalpindi from 20th March 2023 to 19th September 2023 a sample size of 110 was calculated using a WHO sample size calculator with a confirmed diagnosis of ischemic stroke from the age range of 30 years to 80 years of age were recruited in the study. A total of 5ml of the venous sample was obtained after 8 hours of fasting, and centrifuged at 40 Celsius for 15 minutes to analyze the serum lipid profile for obtaining true levels of high-density lipoproteins HDL, and low-density lipoprotein LDL using the auto analyzer machine. The collected data were assessed by data stratification using SPSS and post-stratification Chi-square test was applied and the P value of <0.05 was considered significant. Results: The total cholesterol was deranged in 57.27%, LDL cholesterol was deranged in 60.0%, deranged triglyceride levels in 67.27% and deranged HDL cholesterol in 32.73% of patients. Conclusions: The current study concluded that the frequency of dyslipidemia is significantly high among patients with ischemic stroke. The functions of HDL are dependent on certain factors such as genetics, lifestyle changes, and environmental factors

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