@article{Ehsan_Haresh_Haider Tarar_2023, place={Pakistan}, title={Effectiveness of Intravenous Magnesium Sulfate in Children Presenting to the Emergency Department with Acute Exacerbation of Asthma : Effectiveness of Intravenous Magnesium Sulfate in Asthma}, volume={4}, url={https://thejas.com.pk/index.php/pjhs/article/view/552}, DOI={10.54393/pjhs.v4i02.552}, abstractNote={<p>Asthma is a serious medical condition in the pediatric age group and can have a high mortality, therefore it should be managed effectively. Patients not responding adequately to first line therapy need additional treatment. A few research studies have evaluated the use of intravenous magnesium sulfate in improving respiratory scores in severe acute pediatric asthma but the results have been conflicting. <strong>Objectives</strong>: To determine the benefit of intravenous magnesium sulfate in treating children presenting with worsening of asthma symptoms. <strong>Methods: </strong>A cross-sectional prospective study carried out at the Pediatrics Unit of Zia Uddin University Hospital, Karachi from 1<sup>st</sup> March 2021 to 1<sup>st</sup> March 2022. On the whole, 280 children in the age group 2-12 years with acute worsening of asthma of were selected by non-probability purposive sampling technique, however, children in need of invasive ventilation and those having asthma related complications on radiological investigations were omitted. Chi-square was applied for categorical variables and a p-value <0.05 was considered statistically significant. <strong>Results: </strong>Out of 280 patients who came to the Pediatric Emergency Department with acute severe asthma, 236 (84.3%) patients responded to a single dose of intravenous magnesium sulfate manifested by an improvement in clinical asthma score, while 44 patients (15.7%) did not show improvement. The admission rate to the pediatric intensive care unit was only 12.8%. <strong>Conclusion: </strong>Magnesium sulfate infusion helps improve respiratory symptoms in acute worsening of pediatric asthma.</p>}, number={02}, journal={Pakistan Journal of Health Sciences}, author={Ehsan, Shaista and Haresh, Sindhu and Haider Tarar, Saba}, year={2023}, month={Feb.}, pages={61–65} }