Comparison of Postoperative Analgesic Effectiveness of Bupivacaine and Bupivacaine Plus Dexmedetomidine Wound Infiltration in Abdominal Surgeries under General Anesthesia: Comparison of Bupivacaine and Bupivacaine Plus Dexmedetomidine

Hafsa Tariq; Muhammad Shahid; Muhammad Usman Mohsin; Naima Shakeel; Muhammad Shahzad Afzal; Shahid Rafique

doi:10.54393/pjhs.v5i08.1852

Authors

Hafsa Tariq Department of Anesthesia, District Headquarter Hospital, Sahiwal, Pakistan
Muhammad Shahid Department of Anesthesia, Sahiwal Medical College, Sahiwal, Pakistan
Muhammad Usman Mohsin Department of Anesthesia, Nishtar Medical University, Multan, Pakistan
Naima Shakeel Department of Physiology, Sahiwal Medical College, Sahiwal, Pakistan
Muhammad Shahzad Afzal Department of Surgery, Sahiwal Teaching Hospital, Sahiwal, Pakistan
Shahid Rafique Department of General Surgery, Sahiwal Medical College, Sahiwal, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i08.1852

Keywords:

Post-Operative Analgesia, Bupivacaine, Dexmedetomidine, Wound Infiltration

Abstract

Abdominal surgeries were major surgical procedures that were performed at any teaching hospital. Pain control was a major concern during intra-operative as well as post-operative periods in these patients. Objective: To compare post-operative analgesic effectiveness of bupivacaine and bupivacaine plus dexmedetomidine wound infiltration in abdominal surgeries under General Anesthesia. Methods: This randomized controlled trial was conducted at the Department of Anesthesia, Sahiwal Teaching Hospital Sahiwal from 1^st April, 2024 till 31^st May 2024. Sixty-four patients underwent a pre-operative assessment on the day before surgery. Both Groups received wound infiltration with studied drugs at the end of surgery. After surgery, patients were assessed for pain using a Visual Analog Scale (VAS) and data was collected and analyzed using Statistical Package for the Social Sciences (SPSS) version 26.0. Results: The mean post-operative analgesia duration of the patients on bupivacaine was 11.78 ± 1.64 but the mean post-operative analgesia duration of the patient on bupivacaine plus dexmedetomidine was 19.19 ± 2.49. (2-tailed significance 0.001). The mean opioid consumption in mg of the patients in bupivacaine was 20.69 ± 4.31 but the mean opioid consumption in mg of the patient in bupivacaine plus dexmedetomidine was 10.88 ± 4.53. (2-tailed significance 0.001). In bupivacaine, patients with bradycardia were 0% and patients without bradycardia were 100% but in bupivacaine plus dexmedetomidine, patients with bradycardia were 15.6% and patients without bradycardia were 84.4%. Conclusions: There was a difference in the analgesic effectiveness of dexmedetomidine when added to bupivacaine in wound infiltration in abdominal surgeries.

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