Correlation of Dual-Energy X-Ray Absorptiometry and Quantitative Computerized Tomography in Detection of Osteoporosis among Postmenopausal Women: Dual-Energy X-Ray Absorptiometry and Quantitative Computerized Tomography for Osteoporosis

Shazia Yusuf; Saba Binte Kashmir; Muhammad Afzal Abbasi; Humaira Riaz; Rana Muhammad Haseeb Kamran; Romasa Zeb

doi:10.54393/pjhs.v5i12.1811

Authors

Shazia Yusuf Department of Radiology, Capital Hospital, Islamabad, Pakistan
Saba Binte Kashmir Department of Radiology, Capital Hospital, Islamabad, Pakistan
Muhammad Afzal Abbasi Department of Cardiology, Farooq Hospital, Islamabad, Pakistan
Humaira Riaz Department of Radiology, International University, Rawalpindi, Pakistan
Rana Muhammad Haseeb Kamran Department of Cardiology, Amna Hayat Hospital, Lahore, Pakistan
Romasa Zeb Army Medical College, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i12.1811

Keywords:

Osteoporosis, Quantitative Computerized Tomography, Dual-Energy X-Ray Absorptiometry, Postmenopausal

Abstract

Osteoporosis is a serious health responsibility for clinicians, especially in postmenopausal patients. Dual-energy x-ray absorptiometry is currently the gold standard for the detection of osteoporosis, though its accuracy may be compromised due to concomitant degenerative changes. Objectives: To find out the detection rate of osteoporosis in women who have gone through menopause using both dual-energy X-ray absorptiometry and quantitative computerized tomography and to identify correlations between the two. To evaluate quantitative computerized tomography as a possible future imaging modality that can address the constraints of dual-energy x-ray absorptiometry. Methods: From June 2016 to July 2017, this cross-sectional study was carried out in the radiology Departments of Capital Hospital and Nuclear Medicine, Oncology and Radiotherapy Institute Hospital, Islamabad. With informed consent, seventy postmenopausal women participated. T-scores were calculated for quantitative computerized tomography and dual-energy x-ray absorptiometry, and data analysis, including the Pearson correlation coefficient, was conducted using SPSS-17. Results: The study included postmenopausal women aged 45–70, with menopause lasting over two years. The mean T-scores for quantitative computerized tomography and dual-energy x-ray absorptiometry were -2.4 ± 1.4 SD and -2.1 ± 1.3 SD, respectively. A strong positive correlation was established between quantitative computerized tomography and dual-energy x-ray absorptiometry T-scores (r=0.808; p<0.05). Conclusions: It was concluded that the study showed a constructive association between the T-scores obtained using quantitative computerized tomography and dual-energy x-ray absorptiometry, thus suggesting that quantitative computerized tomography can be used as an alternative to dual-energy x-ray absorptiometry in the detection of osteoporosis.

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