Evaluation of Dyslipidaemia in Patients with Chronic Viral Hepatitis in a Lower Socio-Economic Country: Dyslipidaemia in Chronic Viral Hepatitis

Rakhshinda Jabeen; Aziz Ur Rehman; Ahsan Mobin; Hussain Haroon; Imtiaz Manzoor; Muhammad Ubaid

doi:10.54393/pjhs.v5i05.1493

Authors

Rakhshinda Jabeen Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Aziz Ur Rehman Department of Medicine, Dr.Ruth K M Pfau Civil Hospital, Karachi, Pakistan
Ahsan Mobin Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Hussain Haroon Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Imtiaz Manzoor Department of Medicine and Allied Health Sciences, Chiniot General Hospital, Karachi, Pakistan
Muhammad Ubaid Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v5i05.1493

Keywords:

Dyslipidaemia, Chronic Hepatitis, Body Mass Index, Lipid Profile, Cardiovascular Illness

Abstract

Patients having chronic viral hepatitis do have disturbances in their serum lipid profiles, still the monitoring of dyslipidemia is not a routine part of management in low socio economic countries. Objective: To investigate the status of lipid profile among patients with chronic hepatitis and compare them with non-infected individuals. Methods: A cross-sectional study was done in a Tertiary Care Hospital of Karachi, from 5^th September 2022 to 31^st May 2023. Patients with chronic hepatitis B and C, diagnosed within two years with a body mass index (BMI) of 25-29.9 kg/m² were included. Their comparison was done with non-infected individuals of the same BMI. All patients were evaluated with different parameters of lipid profile along with haemoglobin, alanine aminotransferase, albumin and international normalized ratio. Results: Among 521 participants of the study, the grouping was almost equal. The age range was 12-75 years, with an increased number of females in each group. In comparing the different statuses of lipid profile, each parameter including cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, all were significantly much less in patients with chronic viral hepatitis as compared to controls with a p-value of 0.000 in all. Conclusions: It was concluded that Dyslipidaemia is not common among chronic viral hepatitis patients’ despite being overweight, particularly among patients with child’s class A.

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